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Jun Gu Selected Research

NADPH-Ferrihemoprotein Reductase (Cytochrome P450 Reductase)

1/2020Proximal Tubular Vacuolization and Hypersensitivity to Drug-Induced Nephrotoxicity in Male Mice With Decreased Expression of the NADPH-Cytochrome P450 Reductase.
8/2013Suppression of cytochrome P450 reductase expression promotes astrocytosis in subventricular zone of adult mice.
8/2008Deletion of the NADPH-cytochrome P450 reductase gene in cardiomyocytes does not protect mice against doxorubicin-mediated acute cardiac toxicity.
3/2005In vivo mechanisms of tissue-selective drug toxicity: effects of liver-specific knockout of the NADPH-cytochrome P450 reductase gene on acetaminophen toxicity in kidney, lung, and nasal mucosa.

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Jun Gu Research Topics

Disease

64Neoplasms (Cancer)
01/2022 - 06/2004
24Inflammation (Inflammations)
01/2022 - 02/2003
19Atrial Fibrillation
02/2022 - 09/2011
18Psoriasis (Pustulosis Palmaris et Plantaris)
01/2022 - 12/2007
13Breast Neoplasms (Breast Cancer)
01/2022 - 12/2004
12Infections
04/2021 - 09/2012
9Heart Failure
02/2022 - 10/2016
9Carcinoma (Carcinomatosis)
01/2022 - 09/2003
9Carcinogenesis
01/2022 - 08/2002
9Hepatocellular Carcinoma (Hepatoma)
01/2017 - 04/2006
8Hypertension (High Blood Pressure)
02/2022 - 06/2007
8Neoplasm Metastasis (Metastasis)
10/2021 - 10/2011
8Gallbladder Neoplasms (Gallbladder Cancer)
01/2017 - 06/2012
7Fibrosis (Cirrhosis)
10/2021 - 10/2012
7Ischemia
05/2016 - 02/2003
6Cardiotoxicity
10/2021 - 08/2008
6Type 2 Diabetes Mellitus (MODY)
01/2021 - 09/2011
6Aortic Dissection
09/2020 - 01/2015
6Thrombosis (Thrombus)
06/2019 - 06/2007
6Brain Injuries (Brain Injury)
01/2017 - 08/2009
5Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
10/2020 - 04/2012
5Lung Neoplasms (Lung Cancer)
08/2020 - 04/2013
5Reperfusion Injury
01/2019 - 08/2009
4Cognitive Dysfunction
01/2022 - 03/2007
4Aneurysm (Aneurysms)
01/2021 - 12/2013
4Virus Diseases (Viral Diseases)
01/2021 - 05/2011
4Pain (Aches)
01/2021 - 03/2010
4Left Ventricular Dysfunction
10/2020 - 01/2014
4Hypoxia (Hypoxemia)
07/2020 - 06/2011
4Mitochondrial Diseases (Mitochondrial Disease)
05/2020 - 09/2010
4Stomach Neoplasms (Stomach Cancer)
04/2020 - 01/2013
4Hypertrophy
01/2020 - 02/2003
4Neuroinflammatory Diseases
06/2018 - 02/2014
4Hemorrhage
01/2018 - 10/2012
4Tachycardia (Tachyarrhythmias)
05/2014 - 09/2011
4Substance Withdrawal Syndrome (Withdrawal Symptoms)
02/2004 - 08/2002
3Atherosclerotic Plaque (Atheroma)
04/2022 - 01/2016
3Rupture
04/2022 - 02/2013
3Dermatitis
01/2022 - 01/2019
3COVID-19
10/2021 - 01/2021
3Spinal Cord Injuries (Spinal Cord Injury)
03/2021 - 01/2016
3Skin Diseases (Skin Disease)
01/2021 - 11/2012
3Wounds and Injuries (Trauma)
12/2020 - 05/2008
3Colonic Neoplasms (Colon Cancer)
10/2020 - 12/2004
3Necrosis
08/2020 - 11/2013
3Body Weight (Weight, Body)
07/2020 - 01/2005
3Atherosclerosis
12/2019 - 01/2012
3Pancreatic Neoplasms (Pancreatic Cancer)
01/2018 - 06/2015
3Atrial Remodeling
10/2017 - 12/2013
3Lymphatic Metastasis
09/2017 - 02/2014
3Colorectal Neoplasms (Colorectal Cancer)
02/2017 - 12/2004

Drug/Important Bio-Agent (IBA)

31Proteins (Proteins, Gene)FDA Link
06/2021 - 11/2004
18Messenger RNA (mRNA)IBA
01/2022 - 08/2002
13Biomarkers (Surrogate Marker)IBA
01/2022 - 09/2003
11Pharmaceutical PreparationsIBA
11/2021 - 04/2013
11Biological ProductsIBA
10/2020 - 09/2004
11Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
08/2020 - 11/2007
10Doxorubicin (Adriamycin)FDA LinkGeneric
10/2021 - 06/2004
9MicroRNAs (MicroRNA)IBA
01/2022 - 01/2009
8CytokinesIBA
01/2019 - 12/2007
7DNA (Deoxyribonucleic Acid)IBA
01/2022 - 09/2003
7VaccinesIBA
10/2021 - 12/2008
7Small Interfering RNA (siRNA)IBA
02/2017 - 11/2004
6Mitochondrial DNA (mtDNA)IBA
05/2020 - 01/2016
5Peptides (Polypeptides)IBA
12/2020 - 04/2006
5ResveratrolIBA
01/2018 - 12/2012
5Morphine (MS Contin)FDA LinkGeneric
03/2010 - 08/2002
4Therapeutic UsesIBA
01/2022 - 04/2015
4AntigensIBA
01/2022 - 12/2004
4Antiviral Agents (Antivirals)IBA
04/2021 - 10/2011
4InterleukinsIBA
01/2021 - 01/2016
4Glucose (Dextrose)FDA LinkGeneric
07/2020 - 08/2009
4Adenosine Triphosphate (ATP)IBA
05/2020 - 12/2004
4NADPH-Ferrihemoprotein Reductase (Cytochrome P450 Reductase)IBA
01/2020 - 03/2005
4C-Reactive ProteinIBA
09/2017 - 01/2010
4Interleukin-6 (Interleukin 6)IBA
09/2017 - 03/2011
4EnzymesIBA
05/2015 - 08/2008
4TNF Receptor-Associated Factor 6 (TRAF6)IBA
01/2014 - 04/2009
4NicotineFDA Link
01/2013 - 01/2011
3LipidsIBA
04/2022 - 01/2021
3Imiquimod (Aldara)FDA LinkGeneric
01/2022 - 01/2019
3Interleukin-17 (Interleukin 17)IBA
01/2022 - 01/2020
3RNA (Ribonucleic Acid)IBA
01/2022 - 05/2011
3Coloring Agents (Dyes)IBA
01/2022 - 11/2013
3CateninsIBA
10/2020 - 12/2016
3CollagenIBA
12/2019 - 02/2013
3Glutathione (Reduced Glutathione)IBA
11/2019 - 08/2013
3SolutionsIBA
02/2018 - 04/2015
3Parathyroid Hormone (Parathormone)IBA
01/2018 - 12/2003
3wogoninIBA
11/2017 - 10/2011
3Pioglitazone (Actos)FDA Link
09/2017 - 09/2011
3FlavonoidsIBA
01/2017 - 09/2010

Therapy/Procedure

36Therapeutics
01/2022 - 05/2002
9Catheter Ablation
03/2015 - 09/2011
7Drug Therapy (Chemotherapy)
04/2020 - 01/2012
5Stents
11/2020 - 12/2012
4Aftercare (After-Treatment)
08/2021 - 08/2008
4Spinal Injections
01/2017 - 08/2002
3Percutaneous Coronary Intervention
01/2021 - 01/2010
3Length of Stay
01/2021 - 03/2013